Intermittent Preventive Treatment of Malaria in School-age Children to Decrease Community Transmission

Starting soon · Phase 4

Conditions studied: Malaria

In brief

The CRITICal study aims to estimate the effectiveness of intermittent preventive treatment in school children (IPTsc) with dihydroartemisinin-piperaquine (DP) for reducing community level malaria burden. Given that school-aged children are the primary drivers of transmission, the study hypothesis is that IPTsc will reduce this infectious reservoir and thus the burden of malaria in persons of all ages in surrounding communities.

Key facts

Study ID

NCT07246525

Run by

University of California, San Francisco

People needed

4800

Starts

2026-08-01

Expected to finish

2029-08-31

Last updated by the study team

2026-05-07

Who can join

Age: any, up to 17. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Child currently attending the participating school.
• Agreement of parent/guardian to provide informed consent.
• Agreement of children aged 8-17 years to provide assent.

You may not qualify if…

• Missing school on three consecutive days of the school survey.

Where it is running

• Infectious Diseases Research Collaboration — Kampala, Uganda

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.