Supplementation With Sirtuin Activators in Women With Increased Body Weight
Recruiting now · Not applicable · Has a placebo group
Conditions studied: Obesity & Overweight
In brief
The goal of this clinical trial is to learn if the six-month supplementation with sirtuin activators can affect metabolism in 40-to-65-year old women with increased body weight. The main questions it aims to answer are: Does sirtuin activators affect lipid and carbohydrate metabolism? Does sirtuin activators affect oxydative stress, immune functions and cell ageing? Researchers will compare sirtuin activators to a placebo (a look-alike substance that contains no drug) to see if drug sirtuin activators works to improve metabolic status. Participants will: Take sirtuin activators or a placebo every day for 6 months. Visit the university once every 3 months for checkups and tests.
Key facts
- Study ID
- NCT07245979
- Run by
- Poznan University of Life Sciences
- People needed
- 120
- Starts
- 2025-10-08
- Expected to finish
- 2027-03-01
- Last updated by the study team
- 2026-05-22
Who can join
Age: 40 and older, up to 65. Sex: female. Healthy volunteers: accepted.
You may qualify if…
- females
- age: 40-65 years
- overweight or obese: BMI >25 kg/m2
You may not qualify if…
- males
- BMI < 25 kg/m2
- sirtuin activators administration for 3 months prior to study
- pregnancy or breastfeeding
- recent dieting or being on calorie restricted diet
- receiving pharmacotherapy to treat obesity, diabetes or hyperlipidemia
- post-bariatric surgery
- diabetes
- cancer
- chronic kidney, liver or autoimmune diseases
- alcohol addiction
Where it is running
- Poznan University of Life Sciences — Poznan, Poland (enrolling)
Full record on ClinicalTrials.gov
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