Pistachio Intake and Nutrition-Related Outcomes in Individuals on GLP-1 Therapy

Recruiting now · Not applicable

Conditions studied: Dietary Change, Obesity & Overweight, Food Acceptance

In brief

In this study will look at how eating pistachios every day might affect participants weight, how healthy their diet is, and how they feel when eating. Investigators want to see if adding pistachios to meals for 12 weeks helps participants feel fuller, have more energy, and improve body composition. The study will include adults who have been taking GLP-1 medicines like semaglutide or tirzepatide for at least three months. Investigators also want to see if eating pistachios improves overall diet quality and health markers like tiredness and certain levels in blood.

Key facts

Study ID

NCT07244445

Run by

Ian J. Neeland, MD

People needed

108

Starts

2026-01-29

Expected to finish

2027-12-01

Last updated by the study team

2026-02-20

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Individuals with a BMI ≥30 kg/m2 or with a BMI ≥27 kg/m2 with at least one weight-related comorbidity who have been continuously using semaglutide or tirzepatide for three months for a clinical indication and remain on the therapy at the time of enrollment

You may not qualify if…

• No use or contraindication to use of a GLP-1 RA
• Known allergy to nuts
• Pregnant or breastfeeding
• Incarcerated

Where it is running

• University Hospitals Cleveland Medical Center — Clevland, Ohio, United States (enrolling)

Full record on ClinicalTrials.gov

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