Comparison of FNB to EUS-CNB for Pancreatic Lesions
Starting soon · Not applicable
Conditions studied: Diagnosis of a Pancreaticobiliary Disorder, Biopsy, EUS Guided Biopsy
In brief
The primary aim of this study is to compare the tissue specimen quality and diagnostic accuracy of biopsies obtained with one puncture of a regular 22 FNB G needle and the motorized EUS CNB device of pancreatic lesions. The secondary aims are to compare the rate of blood contamination in the specimens obtained from biopsies of pancreatic lesions and the overall procedure duration. The hypothesis of this study is that the proportion of cases in which a single puncture of the lesion in question delivers adequate diagnostic tissue is higher with the motorized EUS CNB than with the 22 G FNB.
Key facts
- Study ID
- NCT07240818
- Run by
- University of California, Davis
- People needed
- 30
- Starts
- 2026-07-01
- Expected to finish
- 2026-11-01
- Last updated by the study team
- 2026-06-04
Who can join
Age: 18 and older, up to 89. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients who require EUS and tissue sampling of pancreatic solid lesions (size> 2.5 cm)
- Patients who can give consent
You may not qualify if…
- patients without pancreatic lesions
- Pregnant females
- Hematologic and Coagulation disorders (platelets < 50,000/mm3, INR > 2, ANC <1000)
- Patients with acute pancreatitis in the immediate 2 weeks before the procedure (if the lesion to be biopsied is in the pancreas)
- Cardiorespiratory dysfunction that precludes sedation
- patients unable to provide informed consent
- Previous chemotherapy or radiotherapy for a pancreatic neoplasm
- Patients who are not candidates for emergency surgery in case complications arise from the biopsy
Where it is running
- UC Davis Medical Center — Sacramento, California, United States
Full record on ClinicalTrials.gov
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