The Mother-Daughter Project: Merck-4

Starting soon · Not applicable

Conditions studied: Cervical Dysplasia

In brief

This project serves to continue a community-based initiative, known as the Kenya Mother-Daughter Cervical Cancer Eradication Project, or the Mother-Daughter Project (MDP), in the Webuye region of Western Kenya. The MDP project, since its initiation in 2018, has sought to develop a framework for the eradication of cervical cancer through effective screening of adult women and through the vaccination of female children. This project specifically aims to collect additional data on the ability for HR-HPV testing to detect premalignant lesions of the cervix, especially in HIV-infected women, to investigate and identify barriers leading to non-participation in previous MDP efforts, and to examine factors associated with the immune response to HPV vaccination among rural Kenyan girls.

Key facts

Study ID

NCT07240220

Run by

Indiana University

People needed

2500

Starts

2026-02-01

Expected to finish

2028-08-01

Last updated by the study team

2026-01-15

Who can join

Age: 9 and older, up to 49. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• ages 25 through 49 years
• able/willing to sign informed consent
• willing to participate in the community meetings

You may not qualify if…

• pregnant
• Kenyan Girls
• Inclusion Criteria:
• ages 9 through 14 years
• have mother that is able/willing to sign informed consent for vaccination
• can return for the second HPV vaccine dose in 6 - 12 months
• Exclusion Criteria:
• girls who are not willing or unable to return for the second HPV vaccine dose

Where it is running

• Moi University — Eldoret, Kenya

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.