DEXDES Trial: Dexmedetomidine-Desflurane Combination in Laparoscopic Colectomy

Recruiting now · Not applicable

Conditions studied: Colorectal Neoplasms

In brief

This randomized double-blind controlled clinical trial aims to evaluate the efficacy and safety of combining Dexmedetomidine with Desflurane in patients undergoing elective laparoscopic colectomy. The study will assess whether the combination can reduce Desflurane consumption, improve intraoperative hemodynamic stability, and enhance postoperative recovery compared to Desflurane alone.

Key facts

Study ID

NCT07239479

Run by

Tam Anh Research Institute

People needed

40

Starts

2025-12-01

Expected to finish

2027-01-30

Last updated by the study team

2025-12-30

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18-65 years
• ASA Physical Status I-II
• Elective laparoscopic colectomy
• Written informed consent provided

You may not qualify if…

• Severe cardiac, hepatic, or renal disease
• COPD or bronchial asthma
• Chronic opioid or psychotropic medication use
• Atrioventricular block (grade II-III), sick sinus syndrome
• Significant intraoperative bleeding or hemodynamic instability

Where it is running

• Tam Anh TP. Ho Chi Minh General Hospital — Ho Chi Minh City, Ho Chi Minh, Vietnam (enrolling)

Full record on ClinicalTrials.gov

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