TIVA Versus Balanced Anesthesia on Muscle Mass in CRC Surgery

Recruiting now · Not applicable

Conditions studied: Colorectal Cancer (CRC), Sarcopenia

In brief

This study is aimed at clarifying changes in body composition during the perioperative period and identifying risk factors for skeletal muscle mass loss in patients with colorectal cancer. The investigators will asess the impact of the type of anaesthesia (total intravenous anaesthesia/sevoflurane anaesthesia) for colorectal surgery on the muscle function and mass, which will be evaluated using ultrasound, dynamometry and bioimpedance.

Key facts

Study ID

NCT07237438

Run by

Grigore T. Popa University of Medicine and Pharmacy

People needed

40

Starts

2025-09-20

Expected to finish

2026-06-01

Last updated by the study team

2025-11-19

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• adult patients diagnosed with colorectal cancer and scheduled for open colorectal surgery at the Regional Institute of Oncology, Iaşi, Romania

You may not qualify if…

• lack the capacity to consent
• extremity amputation
• paraplegia
• diseases affecting the muscles (such as stroke, lower-limb immobilization from a plaster, neurodegenerative diseases, peripheral neuropathy or muscle dystrophy)
• terminal cancer

Where it is running

• Regional Institute of Oncology, Iaşi, Romania — Iași, Romania (enrolling)

Full record on ClinicalTrials.gov

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