Evaluation of SPM™ Topical Cosmetic Application on Skin Appearance, Hydration, and Barrier Support in Healthy Adults

Starting soon · Not applicable

Conditions studied: Healthy Skin, Skin Hydration

In brief

This is an exploratory, cosmetic-use study evaluating the effects of Super Protein Multifunction (SPM™), a topical peptide-based formulation, on skin appearance, hydration, and barrier-related characteristics in healthy adults. The study aims to collect preliminary biophysical and histologic data on cosmetic skin changes following six weeks of SPM™ use. Participants will apply the product to a designated skin area while a matched contralateral area serves as the untreated comparison site. Skin hydration, transepidermal water loss (TEWL), and tissue markers of skin structure and barrier integrity will be assessed before and after product use. The study includes noninvasive measurements and small punch biopsies at two timepoints.

Key facts

Study ID

NCT07236736

Run by

Biocoz Global Pte. Ltd.

People needed

10

Starts

2026-01-30

Expected to finish

2027-06-30

Last updated by the study team

2025-12-19

Who can join

Age: 20 and older, up to 75. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Generally healthy with no systemic or active dermatologic diseases.
• Willing and able to apply topical product daily for 6 weeks.
• Able to provide written informed consent.
• Willing to undergo skin biopsies and follow study procedures.

You may not qualify if…

• History of skin cancer or other malignancy within the past 10 years.
• Active or chronic dermatologic conditions (e.g., eczema, psoriasis, acne, rosacea).
• Known allergy or sensitivity to components of the investigational product.
• Current use of systemic corticosteroids or immunosuppressants.
• Pregnancy or breastfeeding.
• Any condition that, in the investigator's opinion, would interfere with study participation or pose additional risk.

Where it is running

• Project Quality of Life — West Hollywood, California, United States

Full record on ClinicalTrials.gov

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