Neuropsychological Profile Characterization in Patients With Migraine: Cognitive Functioning and Psychological Variables

Recruiting now

Conditions studied: Migraine, Migraine Disease

In brief

The overall objective is to define the neuropsychological profile of patients with migraine and evaluate its association with: psychological outcome measures (anxiety-depressive symptoms, pain catastrophizing, excessive worry, and coping strategies); the clinical profile of migraine; the prodromal, ictal, or interictal phase of the migraine attack; pharmacological therapy; and detoxification treatment in patients with migraine associated with medication overuse headache.

Key facts

Study ID

NCT07233941

Run by

Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta

People needed

150

Starts

2025-09-01

Expected to finish

2027-05-01

Last updated by the study team

2026-02-11

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Written informed consent.
• Patients aged between 18 and 65 years.
• Diagnosis of migraine according to the International Classification of Headache Disorders (ICHD-3) criteria.
• Patients with a history of migraine for at least one year, to ensure the stability of the condition.
• Stability of ongoing treatment for at least 3 months at baseline.
• Understanding of the Italian language.

You may not qualify if…

• Severe medical or psychiatric conditions (depression, schizophrenia, psychosis) documented by specific previous diagnoses.
• A history of alcohol or drug abuse.
• Primary sensory deficits.

Where it is running

• Fondazione IRCCS Istituto Neurologico Carlo Besta — Milan, Italy (enrolling)

Full record on ClinicalTrials.gov

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