Preoperative Maxillary Nerve Block and Remifentanil Use in Septorhinoplasty

Recruiting now · Not applicable

Conditions studied: Head and Neck Surgery, Plastic Surgery, Rhinoplasty, Pain, Regional Anaesthesia, Nerve Blocks

In brief

Septorhinoplasty is generally a prolonged surgical procedure that frequently involves osteotomy, which may lead to increased intraoperative remifentanil requirements. Moreover, it is often associated with significant bleeding due to the dense capillary network of the nasal region, making the maintenance of low-to-normal blood pressure preferable during surgery. Consequently, achieving stable hemodynamics and providing sufficient analgesia throughout the procedure is essential. This study aims to evaluate the effects of bilateral maxillary nerve block on intraoperative remifentanil consumption and postoperative analgesic efficacy in patients undergoing Septorhinoplasty. A total of 90 patients will be included in the study. Forty-five patients (Group M) will undergo Septorhinoplasty under general anesthesia combined with bilateral maxillary nerve block, while the remaining 45 patients (Group N) will receive general anesthesia alone. In the preoperative phase, a bilateral maxillary nerve block will be performed under ultrasound guidance via the pterygopalatine fossa. During the intraoperative period, total remifentanil consumption will be recorded, alongside assessments of hemodynamic stability, sevoflurane consumption, extubation time, intraoperative bleeding volume, and the satisfaction levels of both the anesthesiologist and the surgeon. In the postoperative period, patient satisfaction, pain scores at 0, 1, 2, 4, 6, 12, 18, and 24 hours as well as at 1 month (measured using the Visual Analog Scale - VAS), additional analgesic requirements, and Quality of Recovery-15 (QoR-15) scores (assessed on preoperative day 1, postoperative day 1, and at 1 month) will be evaluated.

Key facts

Study ID: NCT07233538
Run by: Ankara Etlik City Hospital
People needed: 90
Starts: 2025-08-20
Expected to finish: 2026-12-08
Last updated by the study team: 2025-11-18

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Those with an ASA (American Society of Anesthesiologists) score of I-II
Those with a body mass index (BMI) between 18 and 30
Those scheduled for elective surgery
Those who are fully cooperative Patients who meet the criteria for septorhinoplasty surgery

You may not qualify if…

Conditions that constitute a relative contraindication to regional anesthesia (e.g., coagulation disorders, thrombocytopenia, severe valvular heart disease, local infection at the injection site, allergy to local anesthetic agents)
International Normalized Ratio (INR) > 1.5
Facial paralysis or a history of facial paralysis
History of central nervous system vascular disease
Presence of neuropathy
History of surgery in the region where the block will be performed
American Society of Anesthesiologists (ASA) physical status classification of III or higher
Patients who do not want to participate in the study
Patients with chronic pain or chronic opioid use
Patients with alcohol, substance or drug addiction
Patients with limited cooperation such as dementia, psychiatric disorders
Pregnant and breastfeeding patients will be excluded from the study.
Patients who cannot communicate in their native language will be excluded from the study

Where it is running

Ankara Etlik City Hospital — Ankara, Yenimahalle, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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