Whole Body MRI for Non-invasive Lesion Detection and Therapy Follow-up: Study With Patients With Radiographic axSpA and Non-radiographic axSpA

Recruiting now

Conditions studied: Spondyloarthritis (SpA), Whole-body MRI (WBMRI)

In brief

This study aims to further improve and expand the WB-MRI imaging evaluation cohort of axSpA patients to complete dynamic follow-up and condition assessment. Based on the WB-MRI features, the association of WB-MRI signs with disease activity, inflammation, and structural damage will be analyzed. At the same time, in-depth data mining was conducted and machine learning was used to construct a new axSpA disease activity assessment model based on WB-MRI data, and the accuracy and reliability of the model were clearly evaluated in the discovery cohort and validation cohort.

Key facts

Study ID

NCT07230327

Run by

The First Affiliated Hospital with Nanjing Medical University

People needed

100

Starts

2022-01-01

Expected to finish

2026-12-01

Last updated by the study team

2025-11-17

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Include newly referred patients if:
• The onset of symptoms (back pain/arthritis/enthesitis) < 45 years
• Undiagnosed disease with the following symptoms:
• chronic back pain (duration of back pain more than 3 months) and/or peripheral arthritis (asymmetric arthritis/predominantly of the lower limbs) and/or enthesitis and/or dactylitis

You may not qualify if…

• And diagnosed with non-radiographic or radiographic axial SpA

Where it is running

• The First Affiliated Hospital of Nanjing Medical University — Nanjing, Jiangsu, China (enrolling)

Full record on ClinicalTrials.gov

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