CoGENES Randomized Controlled Trial (RCT)

Running, not enrolling · Not applicable

Conditions studied: Colorectal Carcinoma

In brief

This clinical trial evaluates the effectiveness of trained community engagement specialists for improving communication on colorectal cancer (CRC) prevention and genetic testing among Hispanic/Latino/a/x (H/L) communities. CRC is the second and third leading cause of cancer deaths among United States (US) H/L men and women respectively. Knowledge of inherited germline mutations (changes in a gene that occurs in a sperm or egg cell) is critical for understanding cause of disease and can impact patient treatment options and outcomes. Educational programs and participant engagement approaches focused on H/L individuals considering Latino cultural values, literacy, numeracy, barriers faced, cultural beliefs and attitudes, as well as language of participants are much needed to address these observed disparities. The Community Genetic Navigation Specialists (CoGENES) Program focuses on increasing knowledge, and preparing the CoGENES trainees to help respond to questions, fears, and concerns regarding genetic testing, counseling, biospecimen (sample of urine, blood, or tissue cells) donation and participation in clinical trials to H/L community members, patients and their families. CoGENES may improve communication on colorectal cancer prevention and genetic testing which can help reduce cancer disparities among H/L communities.

Key facts

Study ID

NCT07229443

Run by

University of Southern California

People needed

138

Starts

2024-06-20

Expected to finish

2027-06-20

Last updated by the study team

2026-07-17

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Must be 18 years of age or older
• Ability to understand and the willingness to sign a written informed consent
• Self-reported H/L ethnicity, of any race
• Ability to read, write, and speak Spanish or English
• Resides in Los Angeles County

You may not qualify if…

• Anyone younger than 18 years of age
• Any person with major cognitive deficit or psychiatric impairment
• Any person unable to read and write Spanish or English
• Resides outside of Los Angeles County
• Any person who considers themselves a community health educator or "promotor/a de salud" and/or has taken in the past three years training on colorectal cancer and/or cancer genetics

Where it is running

• USC / Norris Comprehensive Cancer Center — Los Angeles, California, United States

Full record on ClinicalTrials.gov

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