PROMIS and Mobility Evaluation in Sarcoma Patients

Recruiting now

Conditions studied: Sarcoma, Giant Cell Tumor of Bone

In brief

The goal of this is to validate the Patient-Reported Outcomes Measurement Information System (PROMIS) in sarcoma patients undergoing surgery, and to evaluate a novel smartphone app for collecting mobility data. The goals of the study include to: 1. Validate PROMIS as a patient outcome measure in sarcoma 2. Assess the effectiveness of a novel app for administering questionnaires and collecting mobility metrics 3. Compare PROMIS scores and mobility metrics to better evaluate recovery trajectories after surgery Participants will complete PROMIS questionnaires at regularly scheduled intervals using the smartphone app. Questionnaires will be completed pre-operatively and at 6 weeks, 12 weeks, 6 months, and 12 months post-operatively. Additionally, the app will passively track mobility metrics such as daily step count, stairs climbed, and gait parameters to compare with PROMIS scores.

Key facts

Study ID

NCT07227961

Run by

University of Calgary

People needed

800

Starts

2025-07-01

Expected to finish

2031-01-01

Last updated by the study team

2025-11-13

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥ 18 years
• Diagnosis of bone sarcoma, soft tissue sarcoma, or giant cell tumor of bone
• Tumors located in the pelvis, lower extremities, or upper extremities
• Primary or recurrent disease
• Undergoing operative tumor resection, including limb salvage surgery and amputation
• Has an iPhone or Android phone
• Speaks English

You may not qualify if…

• Metastatic bone tumor
• Diagnosis of atypical lipomatous tumor or dermatofibrosarcoma protuberans
• Currently pregnant or planning pregnancy within 6 months
• Unwilling or unable to attend follow-up evaluations
• Cognitive or communication barriers that impede completion of questionnaires

Where it is running

• Foothills Medical Centre, Arthur J Child Comprehensive Cancer Centre, University of Calgary — Calgary, Alberta, Canada (enrolling)
• Mayo Clinic — Phoenix, Arizona, United States
• Mayo Clinic — Rochester, Minnesota, United States
• Mount Sinai Hospital, University of Toronto — Toronto, Ontario, Canada

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.