Human Thalamus in Propagation of Temporal Lobe Seizures and Memory Formation

Enrolling by invitation · Not applicable

Conditions studied: Epilepsy

In brief

The goal of the study is to examine how two key subregions of the human thalamus (ANT and PLV) are connected with other brain structures (Aim 1), how seizures involve the two thalamic subregions differently and how the map of cortico-thalamic ictal propagation matches the intrinsic connectivity maps identified in the same individuals (Aim 2), and the effect of ANT and PLV stimulations on memory formation (Aim 3).

Key facts

Study ID

NCT07226908

Run by

Stanford University

People needed

100

Starts

2024-09-01

Expected to finish

2029-08-01

Last updated by the study team

2025-11-12

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• No medical or surgical contraindication to electrode implantation
• Patient capable of understanding the scope of our project or signing informed consent independently

You may not qualify if…

• Unable to provide informed consent

Where it is running

• Stanford Hospital — Stanford, California, United States

Full record on ClinicalTrials.gov

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