Exercise and Mortality in Middle-Aged and Older Adults

Starting soon

Conditions studied: Overall Survival (All-cause Mortality)

In brief

This protocol is a retrospective study using the observational data of the the Prostate, Lung, Colorectal, and Ovarian (PLCO) screening trial with over 150,000 participants aged 55-74 years to conduct a target trial emulation to examine the association between self-reported exercise and all cause and cause-specific mortality in apparently healthy, middle-aged and older adults. The PLCO includes assessments of participants' exercise level at two timepoints: at randomization into the PLCO trial (Q0) and 5-7 years after randomization into the PLCO (Q1).

Key facts

Study ID
NCT07224659
Run by
City of Hope Medical Center
People needed
19000
Starts
2026-04-01
Expected to finish
2026-08-06
Last updated by the study team
2026-02-04

Who can join

Age: 55 and older, up to 74. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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