Comparing Optimized Models of Primary And Specialist Services for Palliative Care
Enrolling by invitation · Not applicable
Conditions studied: Seriously Ill Hospitalized Patients
In brief
Palliative care (PC) seeks to reduce suffering and improve quality of life for patients with serious illnesses and their families. National guidelines recommend that clinicians either provide palliative care themselves (generalist PC) or consult experts (specialist PC) as a standard part of serious illness care. This pragmatic clinical trial will be conducted with 48 hospitals at two large U.S. health systems and enroll more than 78,000 seriously ill hospitalized patients. Eligibility is determined by a mortality prediction score where enrolled patients have at least a 70% risk of dying within 1 year. Enrollment assessment occurs as close as possible to 36 hours post admission. The 48 hospitals will be randomized to 3 arms: (1) standardized usual care, (2) trained generalist PC, or (3) specialist PC. Generalist clinicians are trained using the Center to Advance Palliative Care (CAPC) online trainings. This pragmatic, hybrid effectiveness-implementation parallel-cluster RCT will assess the comparative effectiveness of triggering generalist PC and specialist PC on several patient-centered outcome measures, and follows a pilot feasibility study. We will collect Patient-Reported Outcomes (PROs) surveys from a random subset of enrolled patients.
Key facts
- Study ID
- NCT07224594
- Run by
- University of Pennsylvania
- People needed
- 78302
- Starts
- 2026-02-16
- Expected to finish
- 2030-07-31
- Last updated by the study team
- 2026-03-12
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age 18 years of age or older; AND Predicted 1-year mortality risk of 70% or greater; AND Admitted to a study hospital.
You may not qualify if…
- Patients who die or have an active or completed discharge order prior to enrollment time OR
- Readmission within 182 days of an eligible encounter OR
- Ineligible service line, with current admission status labeled as: hospice, acute rehabilitation, skilled nursing facility, long-term acute care, psychiatry, obstetrics
Where it is running
- Kaiser Permanente Southern California — Pasadena, California, United States
- Trinity Health — Livonia, Michigan, United States
Full record on ClinicalTrials.gov
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