Feasibility of High Intensity Interval Training in Survivors of Childhood, Adolescent, and Young Adult Hodgkin Lymphoma

Recruiting now · Not applicable

Conditions studied: Hodgkin Lymphoma

In brief

This pilot study evaluates the feasibility of a 12-week high intensity interval training (HIIT) program in survivors of childhood, adolescent, and young adult Hodgkin lymphoma within 24 months of completing treatment. Preliminary efficacy of the HIIT intervention for improved cardiorespiratory fitness, body composition, physical function, autonomic response to exercise, peripheral neuropathy, biological aging markers, and physical activity will also be evaluated. Primary Objective: To determine the feasibility of a 12-week high intensity interval training (HIIT) program in survivors of childhood, adolescent, and young adult Hodgkin lymphoma within 24 months of completing treatment. Feasibility will be assessed by: * Participation Rate: Number of eligible survivors approached who enroll. * Completion Rate: Number of scheduled HIIT sessions attended and number of enrolled participants who complete post-intervention testing.

Key facts

Study ID

NCT07222345

Run by

St. Jude Children's Research Hospital

People needed

20

Starts

2026-06-08

Expected to finish

2029-01-01

Last updated by the study team

2026-06-10

Who can join

Age: 10 and older, up to 25. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Participant has been diagnosed with Hodgkin lymphoma between the ages of 10 to 25 years.
• Participant is between the ages of >10 and <25 years old the time of enrollment.
• Participant has completed treatment (end of chemotherapy for those not receiving radiation therapy or end of radiation therapy) for Hodgkin lymphoma within 24 months prior to enrollment and recovered from any acute treatment-related adverse events.
• Participant has been medically cleared to participate in physical activity.
• Participant verbalizes understanding of directions for use of the web-based platform on the study provided iPad and heart rate monitor.

You may not qualify if…

• Participant has evidence of relapsed disease.
• Participant has a diagnosis of acute heart failure.
• Participant reports currently participating in HIIT training or >420 minutes per week of moderate to vigorous physical activity.
• Female participant who is currently pregnant.

Where it is running

• St. Jude Children's Research Hospital — Memphis, Tennessee, United States (enrolling)

Full record on ClinicalTrials.gov

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