A Clinical Study of Calderasib (MK-1084) With Rosuvastatin and Metformin in Healthy People (MK-1084-016)

Completed · Phase 1

Conditions studied: Healthy

In brief

Researchers want to learn about calderasib when given with rosuvastatin and metformin in healthy people. The goal of this study is to compare the amount of rosuvastatin and metformin in a person's body over time when given with and without calderasib

Key facts

Study ID

NCT07222098

Run by

Merck Sharp & Dohme LLC

People needed

16

Starts

2025-11-19

Expected to finish

2025-12-29

Last updated by the study team

2026-05-06

Who can join

Age: 19 and older, up to 60. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• The main inclusion criteria include but are not limited to the following:
• Has body mass index (BMI) ≥ 18.0 and ≤ 32.0 kg/m\^2

You may not qualify if…

• The main exclusion criteria include but are not limited to the following:
• Has history of cancer (malignancy)
• Positive results for human immunodeficiency virus (HIV), hepatitis B surface antigen (HBsAg), or hepatitis C virus (HCV)

Where it is running

• Celerion ( Site 0001) — Lincoln, Nebraska, United States

Full record on ClinicalTrials.gov

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