Disrupted Sleep and Concurrent Ectopy or Atrial Fibrillation

Recruiting now · Not applicable

Conditions studied: Obstructive Sleep Apnea, Premature Ventricular Contraction (PVC), Atrial Fibrillation (AF), Premature Atrial Contraction

In brief

Whereas the available evidence mostly supports chronic sleep disruption as a risk factor for incident AF, less is known about the near-term risk of a discrete atrial fibrillation (AF) episode following a night of disrupted or poor-quality sleep. This prospective, randomized, case-crossover study aims to examine the acute effects of sleep disruption on clinically relevant cardiac ectopy pertinent to AF.

Key facts

Study ID

NCT07220525

Run by

University of California, San Francisco

People needed

100

Starts

2025-12-15

Expected to finish

2027-06-01

Last updated by the study team

2026-01-23

Who can join

Age: 21 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Are age 21 years or older
• Have a HGNS device implanted for obstructive sleep apnea and followed up at UCSF Health
• Are willing to abstain from using the upper airway stimulation device for no more than two consecutive days as instructed over the 14-day trial period
• Able and willing to provide written informed consent

You may not qualify if…

• Currently pregnant or trying to get pregnant
• Are currently taking class 1 or 3 anti-arrhythmic medications
• Have a history of permanent AF or expected to have continuous AF throughout the study period
• Have congenital heart disease
• Ventricular pacing >40%
• Are unable to read or sign to provide informed consent

Where it is running

• UCSF Medical Center at Parnassus — San Francisco, California, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.