QuantaFlo HD Clinical Validation Study

Recruiting now

Conditions studied: To Assess Cardiovascular Function

In brief

The primary aim of this validation protocol is to assess cardiovascular function through transthoracic echocardiography ("Echo") measurements and the QuantaFlo HD test measuring blood flow at the finger during a forced expiration ("FE"). The study examines whether Echo-measured GLS values greater than -16% correlate with abnormal responses during FE as measured by QuantaFlo HD.

Key facts

Study ID

NCT07219693

Run by

Semler Scientific

People needed

600

Starts

2025-08-21

Expected to finish

2026-06-30

Last updated by the study team

2025-10-23

Who can join

Age: 22 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male and female adult (≥ age 22) subjects with a minimum of 1 of the following:
• A history of Cardiovascular Diseasei or PAD
• Recorded history of at least two of the following
• Hypertension
• Diabetes
• Hyperlipidemia

You may not qualify if…

• Unable to safely perform a forced expiration, or unable to obtain a technically adequate FE test result
• Subjects with a pacemaker or ICD with pacemaker function
• Terminal advanced illness
• Recent cardiothoracic surgery (within 12 months)
• Retinal eye disease with anticoagulants
• History of eye surgery, within 90 days
• Uncontrolled hypertension >180 mmHg systolic pressure or >100 mmHg diastolic pressure
• Subjects with severe tremors

Where it is running

• Pima Heart and Vascular — Tucson, Arizona, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.