A Study to Assess the Adverse Events and How Oral Emraclidine Moves Through the Body of Healthy Elderly Adult Participants

Recruiting now · Phase 1 · Has a placebo group

Conditions studied: Healthy Volunteer

In brief

This study is to assess how oral emraclidine moves through the body of healthy elderly adult participants, and assess adverse events, and tolerability.

Key facts

Study ID

NCT07219030

Run by

AbbVie

People needed

40

Starts

2025-10-08

Expected to finish

2027-03-01

Last updated by the study team

2026-05-12

Who can join

Age: 65 and older, up to 85. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• BMI is ≥ 18.0 to ≤ 32.0 kg/m2 after rounding to the tenths decimal at Screening. BMI is calculated as weight in kg divided by the square of height measured in meters.
• Body weight > 45 kg at the time of screening and upon initial confinement.
• A condition of general good health, based upon the results of a medical history, physical examination, vital signs, laboratory profile and a 12-lead ECG.

You may not qualify if…

• History of any clinically significant cardiac, respiratory (except mild asthma as a child), renal, hepatic, gastrointestinal, genitourinary, immunological, hematologic, neurological or psychiatric disease or disorder, or any other uncontrolled medical illness.
• History of any clinically significant sensitivity or allergy to any medication or food.
• Evidence of dysplasia or history of malignancy (including lymphoma and leukemia) other than successfully treated non-metastatic cutaneous squamous cell, basal cell carcinoma or localized carcinoma in situ of the cervix.

Where it is running

• Altasciences Clinical Los Angeles /ID# 276854 — Cypress, California, United States (enrolling)
• K2 Medical Research, LLC /ID# 276636 — Maitland, Florida, United States (enrolling)
• Clinical Pharmacology Of Miami /ID# 276856 — Miami, Florida, United States (enrolling)
• Acpru /Id# 276996 — Grayslake, Illinois, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.