AZD5335 vs. Mirvetuximab Soravtansine in FRα-high and AZD5335 vs. Chemotherapy in FRα-low Platinum-resistant Ovarian Cancer

Recruiting now · Phase 3

Conditions studied: Epithelial Ovarian Cancer

In brief

The intention of the study is to demonstrate superiority of AZD5335 versus standard of care by assessment of progression-free survival (PFS) in women with high-grade, platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal cancer, expressing high or low FRα levels.

Key facts

Study ID
NCT07218809
Run by
AstraZeneca
People needed
1100
Starts
2025-12-29
Expected to finish
2029-12-27
Last updated by the study team
2026-07-21

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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