Using E-Nose Technology to Track Treatment Response in People With Non-Small Cell Lung Cancer
Recruiting now · Phase 2
Conditions studied: Non-Small Cell Lung Cancer
In brief
The researchers are doing this study to test the ability of a new technology called breathprinting, or electronic nose (E-Nose), to measure changes in certain chemicals in the breath before and after standard neoadjuvant therapy in people with NSCLC.
Key facts
- Study ID
- NCT07218601
- Run by
- Memorial Sloan Kettering Cancer Center
- People needed
- 60
- Starts
- 2025-10-10
- Expected to finish
- 2027-10-01
- Last updated by the study team
- 2026-03-23
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age ≥18
- Untreated clinical stage I NSCLC amenable to upfront surgery
- Untreated stage II to IIIB NSCLC amenable to neoadjuvant treatment followed by surgery
- ECOG Performance Status of ≤2 Of note, the E-nose is a completely noninvasive technology (only breath samples are collected). Therefore, this intervention would have no effects on a developing human fetus. There are therefore no requirements for the study population related to contraception or pregnancy testing.
Where it is running
- Memorial Sloan Kettering Basking Ridge (All Protocol Activities) — Basking Ridge, New Jersey, United States (enrolling)
- Memorial Sloan Kettering Monmouth (All Protocol Activities) — Middletown, New Jersey, United States (enrolling)
- Memorial Sloan Kettering Bergen (All Protocol Activities) — Montvale, New Jersey, United States (enrolling)
- Memorial Sloan Kettering Suffolk-Commack (All Protocol Activities) — Commack, New York, United States (enrolling)
- Memorial Sloan Kettering Westchester (All Protocol Activities) — Harrison, New York, United States (enrolling)
- Memorial Sloan Kettering Cancer Center (All Protocol Activities) — New York, New York, United States (enrolling)
- Memorial Sloan Kettering Nassau (All Protocol Activities) — Uniondale, New York, United States (enrolling)
Full record on ClinicalTrials.gov
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