Radiotherapy Compared to Corticosteroid Injection for Treatment of Hand Osteoarthritis
Recruiting now · Phase 4
Conditions studied: Osteoarthritis Hand, Osteoarthritis Wrist
In brief
The purpose of this research is to compare low-dose radiotherapy to corticosteroid injection for treatment of hand/wrist osteoarthritis.
Key facts
- Study ID
- NCT07217405
- Run by
- Mayo Clinic
- People needed
- 165
- Starts
- 2025-12-19
- Expected to finish
- 2027-10-01
- Last updated by the study team
- 2026-04-24
Who can join
Age: 50 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patient at Mayo Clinic, Rochester, MN
- Age 50 years or older
- Mild, moderate, or severe hand OA (Kellgren and Lawrence classification grade 2, 3, or 4) on hand radiographs within the last 24 months
- Hand OA pain with a minimum VAS score relating to hand pain of ≥40 (on a 100-point scale) when using the affected hand
- Ability to complete study questionnaires
You may not qualify if…
- History of previous surgery to the affected hand(s)
- Autoimmune joint disease such as rheumatoid arthritis or psoriatic arthritis
- Active confounding hand condition such as stenosing tenosynovitis or Dupuytren's contracture
- Recent injury (within last 1 month) to the affected hand causing current pain
- History of crystalline arthritis (gout or pseudogout) flare in the affected hand(s)
- Active use of opioid pain medication(s) or oral steroids within the last 3 months
- Fibromyalgia or central sensitization syndrome
- Hand CSI or other hand injection within the past 3 months
- History of hand LDRT within the past 3 months
- Poorly controlled diabetes (HbA1c > 10%)
- Active infection
- Current pregnancy
Where it is running
- Mayo Clinic in Rochester — Rochester, Minnesota, United States (enrolling)
Full record on ClinicalTrials.gov
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