A Study of LY3938577 in Participants With Type 2 Diabetes Previously Treated With Basal Insulin

Running, not enrolling · Phase 2

Conditions studied: Diabetes Mellitus, Type 2

In brief

The purpose of this study is to see how well LY3938577 works and how safe it is compared to degludec in people with type 2 diabetes. Participation in the study will last about 26 weeks.

Key facts

Study ID

NCT07215312

Run by

Eli Lilly and Company

People needed

100

Starts

2025-10-13

Expected to finish

2026-12-01

Last updated by the study team

2026-07-13

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Have type 2 diabetes
• Are receiving ≥20 units of basal insulin per day and ≤55 units/day and ≤1.5 units/kg/day at screening
• Have hemoglobin A1c (HbA1c) 7.5% to 10.5% inclusive
• Have a body mass index (BMI) of 20 or higher and less than 35 kilograms per square meter (kg/m2)

You may not qualify if…

• Have type 1 diabetes

Where it is running

• Tucson Clinical Research Institute — Tucson, Arizona, United States
• Encompass Clinical Research — Spring Valley, California, United States
• University Clinical Investigators, Inc. — Tustin, California, United States
• Tampa Bay Medical Research — Clearwater, Florida, United States
• Encore Medical Research — Hollywood, Florida, United States
• Clinical Research of Central Florida — Lakeland, Florida, United States
• Encore Medical Research - Weston — Weston, Florida, United States
• Iowa Diabetes and Endocrinology Research Center — West Des Moines, Iowa, United States
• Washington University School of Medicine — St Louis, Missouri, United States
• Accellacare - Wilmington — Wilmington, North Carolina, United States
• AMR Clinical — Norman, Oklahoma, United States
• Tribe Clinical Research, LLC — Greenville, South Carolina, United States
• Holston Medical Group — Bristol, Tennessee, United States
• Texas Diabetes & Endocrinology, P.A. — Austin, Texas, United States
• Velocity Clinical Research, Dallas — Dallas, Texas, United States
• Juno Research — Houston, Texas, United States
• Southern Endocrinology Associates — Mesquite, Texas, United States
• Consano Clinical Research, LLC — Shavano Park, Texas, United States
• Texas Valley Clinical Research — Weslaco, Texas, United States
• Chrysalis Clinical Research — St. George, Utah, United States
• Cicemo Srl — Buenos Aires, Argentina
• CIPREC — Buenos Aires, Argentina
• Mautalen Salud e Investigación — Buenos Aires, Argentina
• Centro Medico Dra. Laura Maffei- Investigacion Clinica Aplicada — Buenos Aires, Argentina
• Instituto Centenario — CABA, Argentina

Full record on ClinicalTrials.gov

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