Follicular Fluid microRNAs in Ovarian Aging and Reproduction

Recruiting now

Conditions studied: Ovarian Aging, In Vitro Fertilisation (IVF) Treatment, InVitro Fertilization, In Vitro Fertilization Outcome

In brief

The purpose of this study is to investigate the role of exosomal microRNAs (miRNAs) in follicular fluid (FF) as biomarkers of ovarian aging and predictors of in vitro fertilization (IVF) outcomes. The goal is to identify noninvasive molecular markers that correlate with oocyte quality and reproductive potential, particularly in women of advanced maternal age.

Key facts

Study ID

NCT07214246

Run by

University of Central Florida

People needed

100

Starts

2025-09-22

Expected to finish

2026-09-01

Last updated by the study team

2025-10-09

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Women undergoing IVF treatment due to male factor infertility or nonovarian causes.
• Age groups: younger women <31 years and older women >38 years.
• Regular menstrual cycles.
• Willing and able to provide informed consent.

You may not qualify if…

• Minors (under 18 years) and women aged 32-37 years
• Diagnosis of polycystic ovarian syndrome (PCOS).
• History of recurrent pregnancy loss.
• Presence of endometriosis.
• Diagnosis of ovarian insufficiency.
• Metabolic disorders (e.g., diabetes).
• History of ovarian surgery or chemotherapy.
• Any condition that might impact follicular fluid quality or IVF outcomes.

Where it is running

• University of Central Florida — Orlando, Florida, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.