Novel DBS Device in Parkinson's Disease
Completed · Not applicable
Conditions studied: Parkinson's Disease (PD)
In brief
The purpose of this research is to test a new recorder that can measure brain activity when stimulation is turned on during deep brain stimulation (DBS) surgery. To continue to improve DBS therapy, the investigators need to better understand the changes in the brain of people with Parkinson's disease (PD). They also need to know how this is affected by DBS. Current recorders measure activity immediately after, but not during, stimulation. Standard-of-care DBS already includes the electrical recording of brain activity during movement of arms and legs. These recordings occur during the microelectrode recording part of the surgery and are used by the medical team to determine where to place the DBS electrode.
Key facts
- Study ID
- NCT07213999
- Run by
- University of Minnesota
- People needed
- 1
- Starts
- 2022-07-01
- Expected to finish
- 2022-07-02
- Last updated by the study team
- 2025-10-09
Who can join
Age: 22 and older, up to 75. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Has unilateral STN or GPi DBS and is approved to undergo second or contralateral side implantation;
- Diagnosis of idiopathic PD;
- A history of a good response to levodopa (carbidopa/levodopa) defined as at least a 30% improvement in motor unified Parkinson's disease rating scale (UPDRS) score;
- DBS surgery at UMN is planned as part of routine clinical care.
You may not qualify if…
- Other significant neurological disorder
- History of dementia
- Patients with post-operative complications or adverse effects (e.g. ON stimulation dystonias) that affect patient safety or confound the experiment will be excluded from further study
- Pregnant women
Where it is running
- University of Minnesota Medical Center — Minneapolis, Minnesota, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.