Linking Diet, Inflammation, Gut Microbiota, and Sarcopenia: A Cross-Sectional Study

Recruiting now

Conditions studied: Sarcopenia

In brief

Based on the analysis of dietary characteristics, gut microbiota diversity, and composition, this study investigates the relationships between the dietary inflammatory potential, gut microbiota, and sarcopenia. Furthermore, it explores the mediating role of gut microbiota in the association between the dietary inflammatory index and the risk of sarcopenia. The findings are expected to provide insights into the mechanisms through which dietary inflammation influences the development and progression of sarcopenia, and to offer a basis for dietary and nutritional interventions aimed at preventing or managing this condition.

Key facts

Study ID

NCT07211321

Run by

Jianhua Ma

People needed

1220

Starts

2024-04-16

Expected to finish

2025-12-31

Last updated by the study team

2025-10-07

Who can join

Age: 60 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Permanent residents of the community aged 60 years or older.
• Continuous residence duration in the community for more than 5 years.

You may not qualify if…

• Taking medications known to affect muscle function (e.g., corticosteroids, protein supplements, muscle enhancers).
• Requiring walking assistance or having severe cognitive impairment that would preclude successful completion of assessments including bioelectrical impedance analysis (BIA), gait speed measurement, and handgrip strength testing.
• Presence of a cardiac pacemaker, which contraindicates BIA measurement.
• Diagnosis of one or more chronic diseases that significantly limit dietary intake.

Where it is running

• Lanzhou university — Lanzhou, Gansu, China (enrolling)

Full record on ClinicalTrials.gov

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