Longitudinal Autonomic Characterization as a Predictor for Secondary Medical Complications Post-SCI

Recruiting now · Not applicable

Conditions studied: Spinal Cord Injuries

In brief

The purpose of this research is to learn about how the body is able to balance changes in blood pressure, how that changes over time, and how these changes impact a participant's risk of developing medical problems.

Key facts

Study ID

NCT07210437

Run by

Mayo Clinic

People needed

18

Starts

2026-01-31

Expected to finish

2028-06-01

Last updated by the study team

2026-05-28

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 18-75 years old
• Spinal cord injury with neurological level of injury from C6-T12
• ASIA Impairment Scale A-D.
• Either acute SCI <3 months prior (n=10) or chronic SCI (>1 year since injury, n=8).

You may not qualify if…

• Symptoms of cardiovascular (including, but not limited to: hypertension, stroke, chest pain, etc.), respiratory, peripheral neurological or autonomic disease (particularly diabetes mellitus requiring treatment);
• Women who are pregnant or lactating
• Taking or being administered a medication known to potentially have adverse interactions with phenylephrine
• In the judgement of the principal investigator, any illness or condition that will interfere with the patient's ability to comply with the protocol, compromise patient safety, or interfere with the interpretation of the study results.

Where it is running

• Mayo Clinic — Rochester, Minnesota, United States (enrolling)

Full record on ClinicalTrials.gov

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