AI-Guided Left Bundle Branch Area Pacing

Recruiting now · Not applicable

Conditions studied: Heart Failure

In brief

The purpose of this study is to compare the effectiveness of AI-guided LBBAP versus conventional LBBAP (not AI-guided) in improving CRT response rates and clinical outcomes.

Key facts

Study ID

NCT07206602

Run by

Mayo Clinic

People needed

224

Starts

2026-01-23

Expected to finish

2027-11-01

Last updated by the study team

2026-02-18

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age: 18 years or older.
• Left Ventricular Ejection Fraction (LVEF): <50% within 6 months prior to enrollment.
• QRS Duration: Resting QRS duration ≥ 130 ms on ECG OR anticipated right ventricular pacing > 40% OR device in place with right ventricular pacing > 40% within 6 months prior to enrollment.
• Medical Therapy: Optimized on guideline-directed medical therapy for heart failure.
• AI-ECG probability of low LVEF: >0.5

You may not qualify if…

• Age less than 18 years old
• Inability to follow-up
• Pregnancy

Where it is running

• Mayo Clinic in Rochester — Rochester, Minnesota, United States (enrolling)

Full record on ClinicalTrials.gov

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