Effects of Transcranial Photobiomodulation in ADHD

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Attention Deficit Hyperactivity Disorder

In brief

The investigators have previously shown that non-invasive methods of brain stimulation such as the administration of transcranial infrared light to the prefrontal cortex (PFC) can result in improvements to cognition and emotion as well as brain oxygenation. This method is called transcranial photobiomodulation (tPBM). The investigators hypothesize that tPBM can improve cognition and brain oxygenation in adults with attention deficit hyperactivity disorder (ADHD). The investigators will investigate the effects of repeated tPBM sessions on cognitive functioning in adults with ADHD. Specifically, the investigators hypothesize that participants that receive tPBM will show improvements in response control, sustained attention, and working memory, as well as improvements in prefrontal hemodynamics and a reduction in ADHD symptoms.

Key facts

Study ID

NCT07203092

Run by

Francisco Gonzalez-Lima, PhD

People needed

140

Starts

2025-09-01

Expected to finish

2027-12-01

Last updated by the study team

2026-06-22

Who can join

Age: 18 and older, up to 44. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• English-speaking
• Adults of any sex
• Age range: 18-44 years
• Any ethnic/racial background
• Medical history of ADHD
• Participants may either be on a stable ADHD medication regimen (with no changes within two weeks prior to the study) or not taking medication.

You may not qualify if…

• Currently pregnancy
• Any sham or active photobiomodulation treatment within the past five weeks.

Where it is running

• The University of Texas at Austin — Austin, Texas, United States (enrolling)

Full record on ClinicalTrials.gov

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