The Effect of Different Flap Closure Techniques on Postoperative Morbidity in Impacted Third Molar Surgery

Recruiting now · Not applicable

Conditions studied: Impacted Mandibular Third Molar, Postoperative Morbidity, Oral Surgery

In brief

1\. ABSTRACT This study is a randomized controlled trial comparing the clinical efficacy and safety of four different flap closure techniques in reducing postoperative morbidity (pain, swelling, trismus, wound healing) and improving patient quality of life (GOHAI) following impacted mandibular third molar extraction. The methods include conventional suturing, sutureless technique, surgical drain, and cyanoacrylate tissue adhesive, which are commonly used in oral surgery practice. The study aims to scientifically evaluate the effects of each method on patients and to determine the most appropriate clinical approach.

Key facts

Study ID

NCT07198282

Run by

Recep Tayyip Erdogan University

People needed

148

Starts

2026-05-08

Expected to finish

2026-08-30

Last updated by the study team

2026-06-09

Who can join

Age: 18 and older, up to 40. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients aged 18-40 years.
• Patients with no systemic diseases (ASA I).
• Patients with impacted mandibular third molars indicated for extraction, with bone and/or mucosal retention, in similar positions (Pell \& Gregory Class 2, Position B; Winter classification vertical or mesioangular).

You may not qualify if…

• Patients classified as ASA II, III, or IV.
• Known allergy to anesthetic solutions.
• Allergy to acrylate.
• Pregnant or breastfeeding women.
• Individuals with tobacco use ≥10 cigarettes/day.
• Alcohol users.
• Patients using antiplatelet agents.
• Patients using anticoagulants.
• Patients with coagulation disorders.
• Patients with immunosuppressive diseases or receiving immunosuppressive therapy.
• Patients with acute pain or local infection at the surgical site.

Where it is running

• Recep Tayyip Erdoğan University, Faculty of Dentistry, Department of Oral and Maxillofacial Surgery — Rize, Rize Province, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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