Identification of Brain Injury Using Portable MRI

Recruiting now

Conditions studied: Cardiac Arrest (CA), Hypoxic-Ischemic Brain Injury

In brief

The goal of this study is to look for brain injury in patients who had a cardiac arrest, using portable brain imaging. The portable nature of this test will also allow for serial imaging so the investigators can understand how brain injury changes over days. The results of this study may allow for bedside imaging to be available at centers without specialized imaging centers and may identify markers of brain injury that help to select the patients most likely to benefit for clinical trials.

Key facts

Study ID

NCT07197918

Run by

Yale University

People needed

60

Starts

2025-12-02

Expected to finish

2027-04-01

Last updated by the study team

2026-01-27

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Unresponsive immediately after ROSC from IHCA or OHCA
• Age ≥ 18 years of age
• Conventional MRI is clinically indicated
• Treatment with temperature control

You may not qualify if…

• MRI contraindication according to the American Heart Association guidelines
• Inability to tolerate supine positioning for 30 minutes
• Diffuse loss of grey-white differentiation and sulcal effacement on head computed tomography within 6 hours of ROSC

Where it is running

• Yale New Haven Hospital — New Haven, Connecticut, United States (enrolling)

Full record on ClinicalTrials.gov

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