Valvular Heart Disease in Women Registry

Recruiting now

Conditions studied: Valve Disease, Heart, Gender Bias, Guideline Adherence, Guideline Implementation, Disparities, Registry

In brief

Valvular heart disease (VHD) is a major global health issue. Untreated rheumatic heart disease persists in many regions, preventable with timely care. Higher-income countries face rising calcific valve disease from aging, worsened by VHD complications, like infective endocarditis, resulting in higher morbidity/mortality. Gender disparities in VHD remains understudied, despite inequalities in risks, diagnosis, and treatment. Prevalence varies by gender, but uneven diagnostics and therapies obscure realities. This registry will examine gender disparities from hospital admission to first outpatient follow-up, recruiting both men and women to investigate and report the study objectives.

Key facts

Study ID

NCT07196930

Run by

Valvular Heart Disease in Women Registry

People needed

800

Starts

2024-04-01

Expected to finish

2030-12-01

Last updated by the study team

2025-09-29

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patients with diagnosis of any VHD according to the current ESC guidelines.
• Admission to the VHD-W Registry collaborating center.

You may not qualify if…

• Age less than 18 years old.
• Inability to provide informed consent per local institutional and regulatory requirements.

Where it is running

• Aswan Heart Centre — Aswān, Egypt (enrolling)
• University of Lisbon — Lisbon, Portugal (enrolling)

Full record on ClinicalTrials.gov

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