Percutaneous Ultrasound-guided Neuromodulation to Improve Gait Rehabilitation in Patients Who Have Suffered a Stroke.

Recruiting now · Not applicable

Conditions studied: Ictus, Gait Disorders, Neurologic

In brief

The goal of this clinical trial is to learn if percutaneous ultrasound-guided neuromodulation (NMP-e) can improve gait rehabilitation in adults who have suffered a stroke. The main questions it aims to answer are: * Does NMP-e improve walking speed in stroke survivors? * Does NMP-e enhance muscle strength, functional mobility, reduce spasticity, improve balance, and increase health-related quality of life? Researchers will compare the addition of NMP-e to conventional physiotherapy versus conventional physiotherapy alone to see if the intervention provides additional benefits in gait rehabilitation and other functional outcomes. Participants will: * Continue their regular physiotherapy treatment consisting of passive and active-assisted mobilizations and strength exercises. * Receive NMP-e targeting the sciatic nerve at mid-thigh and the common peroneal nerve at the fibular head (experimental group only). * Undergo stimulation with an electrostimulator at 10 Hz for 10 seconds per trial, repeated 10 times, with intensity adjusted for comfort. * Be evaluated before the intervention, immediately after, and one week later using: * 10-Meter Walk Test for gait speed * Dynamometry for ankle plantarflexor and dorsiflexor strength * Time Up and Go test for functional mobility * Modified Modified Ashworth Scale for spasticity * Berg Balance Scale for balance * EuroQoL-5 Dimensions for health-related quality of life Participants must be adults aged 18-70, able to walk 10 meters without assistance, currently receiving physiotherapy, and able to provide informed consent. Key exclusions include pregnancy, bleeding disorders, needle allergies, systemic inflammatory disorders, or recent invasive physiotherapy. This randomized controlled trial will be conducted at ATECE, \*\*a Spanish association dedicated to the care and rehabilitation of individuals with acquired brain injury\*\*, where participants will be recruited and receive their interventions. The study aims to evaluate the potential of NMP-e as an adjunctive therapy for improving gait and related functional outcomes in subacute and chronic stroke patients.

Key facts

Study ID

NCT07196878

Run by

Alejandro Martín García

People needed

30

Starts

2025-09-15

Expected to finish

2026-12-31

Last updated by the study team

2026-06-12

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Be between 18 and 70 years of age;
• Have suffered a stroke (CVA);
• Be in the subacute or chronic phase of the disease;
• Be able to walk 10 meters without assistance from another person;
• Currently be undergoing physiotherapy with conservative techniques;
• Be able to understand the technique being applied;
• Sign the informed consent form.

You may not qualify if…

• Belonephobia (fear of needles);
• Allergy to needles or metals;
• Presence of uncontrolled coagulopathies;
• Presence of uncontrolled arterial disease;
• Pregnancy;
• Dermatological disorders;
• Presence of diseases such as systemic inflammatory disorders (e.g., rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, or septic arthritis);
• Presence of diseases such as tumors, cancer, or metastases;
• Having received invasive physiotherapy treatment in the last 4 weeks.

Where it is running

• Universidad de Zaragoza — Zaragoza, Aragon, Spain (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.