Mental Imagery on Upper Extremity Skills

Recruiting now · Not applicable

Conditions studied: PARKINSON DISEASE (Disorder), Mental Imagery, Motor Imagery

In brief

Parkinson's disease (PD) is the second most common neurodegenerative disease, characterized pathologically by the progressive loss of dopaminergic neurons in the substantia nigra and clinically by the presence of motor symptoms such as bradykinesia, resting tremor, and/or rigidity. Among the motor deficits frequently observed in PD, patients are known to frequently report difficulties with manual dexterity. Many upper extremity and manual dexterity deficits are present in PD. Motor imagery (MI) is the imaginal execution of motor activities or the activation of specific muscles in the absence of any explicit feedback. This area of rehabilitation has been shown to be effective in improving and developing motor skills in many neurological conditions where patients exhibit motor recognition and execution impairments. MI can be applied at all stages of recovery from PD, is highly effective in movement-related pathologies, and can be performed independently.There is sufficient evidence that MI improves motor performance and learning in individuals with neurological disorders such as multiple sclerosis, stroke, and spinal cord injury. The study was designed to investigate the immediate effects of mental imagery, which is thought to be effective in controlling difficulties in planning and initiating movements in PD, on upper extremity skills. Therefore, the aim of this study was to determine the effect of mental imagery on upper extremity skills in PD.

Key facts

Study ID

NCT07193303

Run by

Kahramanmaras Sutcu Imam University

People needed

30

Starts

2026-05-15

Expected to finish

2027-01-30

Last updated by the study team

2026-07-14

Who can join

Age: 40 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Healthy individuals aged 40-75 years, diagnosed with idiopathic PD according to the UK Parkinson's Disease Association Brain Bank criteria by a specialist neurologist, with a Modified Hoehn \& Yahr (m-HY) scale stage ≤4, and with a Mini Mental State Examination score of ≥24 for those with training and ≥18 for those without training, and with no known disease, volunteered to participate in the study.
• PD individuals with no other known neurological and/or systemic disease
• PD individuals without any upper extremity contractures

You may not qualify if…

• Individuals with diagnosed and/or treated psychiatric illnesses who are considered unable to complete the tests.
• Individuals who is taking neuroleptic medications or antidepressants.
• Individuals with orthopedic conditions that interfere with manual dexterity tests, such as severe dyskinesia, carpal tunnel syndrome, tendon injuries, or finger amputations; rheumatological conditions such as rheumatoid arthritis and osteoarthritis; and individuals with any neurological condition other than PD.

Where it is running

• Kahramanmaraş Sütçü imam University — Kahramanmaraş, Onikişubat, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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