MAGNIFY - Pulmonary Magnetic Resonance Imaging for Cystic Fibrosis
Recruiting now
Conditions studied: Cystic Fibrosis (CF)
In brief
This research study is looking at new ways of measuring the function of the lungs in patients with cystic fibrosis. This study is using the most advanced methods for measuring lung function including 2 tests called hyperpolarised gas magnetic resonance imaging (HP MRI) and multiple breath washout (MBW), to better understand changes in the lungs over time. HP MRI involves taking pictures of the air in your lungs after breathing in a harmless gas (xenon). MBW is a breathing test used to calculate something called the lung clearance index (LCI). By measuring these tests on the same day, alongside standard lung function tests, we aim to understand lung function in greater detail than ever before.
Key facts
- Study ID
- NCT07192679
- Run by
- Sheffield Teaching Hospitals NHS Foundation Trust
- People needed
- 60
- Starts
- 2024-02-21
- Expected to finish
- 2029-06-30
- Last updated by the study team
- 2026-04-29
Who can join
Age: 1 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- University of Sheffield MRI Unit — Sheffield, United Kingdom (enrolling)
Full record on ClinicalTrials.gov
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