To Compare Post-Extraction Use of a Novel Ethylenediaminetetraacetic Acid (EDTA) Post-operative Mouth Rinse and Daily Use EDTA Mouth Rinse and Standard 0.12% Chlorhexidine (CHX) Post-operative Mouth Rinse and Daily Use Essential Oil (EO) Mouth Rinse.
Recruiting now · Not applicable
Conditions studied: Extraction Sites After Removal and Bone Replacement Grafting at Extraction Sockets of Dentally Hopeless Single-rooted Teeth
In brief
This study will compare commercially available, commonly used mouth rinses (0.12% chlorhexidine (CHX) vs. Ethylenediaminetetraacetic acid (EDTA)) for immediate post-operative and daily antiseptic use after tooth extraction and ridge preservation grafting followed by daily use of commercially available an essential oil (EO) mouthrinse and EDTA mouthrinse.
Key facts
- Study ID
- NCT07191262
- Run by
- University of Alabama at Birmingham
- People needed
- 40
- Starts
- 2026-03-02
- Expected to finish
- 2028-12-01
- Last updated by the study team
- 2026-03-20
Who can join
Age: 18 and older, up to 85. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Able to read and provide informed consent in English
- At least 18 years old
- Established and registered patient of the UAB School of Dentistry
- Patients presenting with one single rooted tooth determined to need extraction and simultaneous ridge preservation bone grafting for future dental implant placement.
- Presence of periodontally healthy, non-carious neighboring teeth and/or healthy restored dental implants on either side of the tooth planned for extraction.
- No anticipated need for surgical and/or endodontic care at teeth adjacent to the proposed surgical site during the study period.
You may not qualify if…
- Non-English speaking
- Age less than 18 years old or older than 85 years old
- Smokers/nicotine users (>10 cigarettes or equivalent/day)
- Patients with systemic pathologies or conditions contraindicating oral surgical procedures or adversely affecting wound healing
- Multiple adjacent teeth require extraction and grafting
- Absence of adjacent teeth/implants on either side of the tooth to be extracted.
- Documented or suspected allergy or sensitivity to any study product
Where it is running
- University of Alabama at Birmingham — Birmingham, Alabama, United States (enrolling)
Full record on ClinicalTrials.gov
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