Weight Bearing After Pelvis and Acetabulum Fracture Fixation

Starting soon · Not applicable

Conditions studied: Pelvis Fractures, Acetabulum Fractures

In brief

The goal of this study to determine if a randomized clinical trial of immediate versus delayed weight bearing after undergoing surgical fixation of a pelvis or acetabulum fracture is feasible. The main questions it aims to answer are: Are surgeons willing to allow inclusion of their patients into such a trial? Are patients willing to participate in such a trial? Will patients be compliant with assigned weight bearing status in such a trial? Can good patient follow-up be obtained in such a trial? Is participation in such a trial safe? Patients from 7 medical centers will be enrolled, and randomized to immediate weight bearing as tolerated (WBAT) versus delayed WBAT (for 6-12 weeks). Feasibility metrics revolving around enrollment, follow-up, and documentation will be monitored, as well as medical and surgical complications. This pilot study will help inform feasibility and design of a larger definitive multicenter randomized controlled trial (RCT) on this topic.

Key facts

Study ID

NCT07189156

Run by

University of Mississippi Medical Center

People needed

200

Starts

2025-10-01

Expected to finish

2028-12-01

Last updated by the study team

2025-09-23

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults 18 years old and above
• Patients with surgically treated pelvis or acetabulum fractures

You may not qualify if…

• Presence of fractures to the ipsilateral or contralateral lower extremity that would preclude WBAT on the surgically repaired pelvis/acetabulum fracture
• Presence of upper extremity injury that would limit weight bearing using an assistive device such as a walker or crutches
• Severe injuries to other body systems that would prevent patient from being able to comply with weight bearing protocol
• Presence of significant psychiatric or cognitive disorder or disability that would prevent patient from being able to comply with weight bearing protocol
• Pre-injury non-ambulatory status
• Suspected issues with follow-up
• Language barriers precluding obtaining adequate informed consent

Where it is running

• University of Alabama Birmingham — Birmingham, Alabama, United States
• Arrowhead Regional Medical Center — Colton, California, United States
• Indiana University Health — Indianapolis, Indiana, United States
• R Adams Cowley Shock Trauma Center - University of Maryland — Baltimore, Maryland, United States
• University of Mississippi Medical Center — Jackson, Mississippi, United States
• Inova Medical Group — Fairfax, Virginia, United States
• Vancouver General Hospital - University of British Columbia — Vancouver, British Columbia, Canada

Full record on ClinicalTrials.gov

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