Exercise as Medicine for Pediatric Chronic Pain

Starting soon · Not applicable

Conditions studied: Chronic Pain, Child, Adolescent

In brief

Youth with chronic pain struggle to go to school, play sports, or spend time with friends and family due to pain. Medications are often ineffective, and aerobic exercise may improve both pain sensitivity and participation in valued life activities. This study will be the first to examine the impact of a single session of intense aerobic exercise on pain sensitivity measures in youth with and without chronic pain syndromes to help determine if aerobic exercise can improve pain and functioning.

Key facts

Study ID

NCT07182006

Run by

Boston Children's Hospital

People needed

66

Starts

2026-04-01

Expected to finish

2027-03-30

Last updated by the study team

2025-09-19

Who can join

Age: 10 and older, up to 17. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Primary or secondary chronic pain syndrome

You may not qualify if…

• Allodynia (pain with light touch) at testing sites (non-dominant forearm)
• Self-reported use of opioids in last week
• Comorbid condition for which exercise is deemed unsafe by a physician or the (Physical Activity Readiness Questionnaire+) PARQ+
• unable to safely ambulate on a treadmill

Where it is running

• Boston Children's Hospital at 2 Brookline Place — Brookline, Massachusetts, United States

Full record on ClinicalTrials.gov

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