PENG vs L-ESPB With S-ESPB for Analgesia in Total Hip Arthroplasty
Recruiting now · Phase 4 · Has a placebo group
Conditions studied: Hip Osteoarthritis, Hip Arthropathy, Hip Pain Chronic
In brief
The goal of this clinical trial is to evaluate whether different types of regional anesthesia can improve pain control and functional recovery after total hip arthroplasty in adult patients undergoing elective hip replacement surgery. The main questions it aims to answer are: Does the PENG block reduce opioid use in the first 48 hours after surgery more effectively than the combined L-ESPB + S-ESPB technique? Which method provides better pain relief, preserves muscle strength, and supports earlier mobilization? Researchers will compare the Pericapsular Nerve Group (PENG) block with the combination of Lumbar and Sacral Erector Spinae Plane Blocks (L-ESPB + S-ESPB) to see which provides better pain control, fewer side effects, and faster recovery. Participants will: Be randomly assigned to receive one of the two types of ultrasound-guided regional anesthesia Undergo standard hip replacement surgery under spinal anesthesia Be monitored for pain scores, opioid use, time to first walking, muscle strength, satisfaction, and side effects over the first 48 hours after surgery.
Key facts
- Study ID
- NCT07180979
- Run by
- Poznan University of Medical Sciences
- People needed
- 90
- Starts
- 2025-09-15
- Expected to finish
- 2026-11-30
- Last updated by the study team
- 2026-05-07
Who can join
Age: 65 and older, up to 100. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age ≥ 65 years
- ASA physical status I-III
- Elective unilateral THA via posterior or lateral approach
- Informed consent provided
You may not qualify if…
- Allergy to study drugs (ropivacaine, dexamethasone)
- Chronic opioid use (>30 MME/day)
- Coagulopathy or infection at the injection site
- BMI > 40 kg/m²
- Pre-existing motor weakness or neuropathy in the affected limb
- Cognitive impairment precluding informed consent
Where it is running
- Poznan University of Medical Sciences — Poznan, Poland (enrolling)
Full record on ClinicalTrials.gov
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