Menstrual Cycle TMS Plasticity Pilot

Recruiting now

Conditions studied: Cortical Activation

In brief

Aim 1: Assess how menstrual cycle phase affects motor cortex plasticity in females. Aim 2: Compare motor cortex plasticity between males and females across the same time points, identifying potential sex differences in TMS response. Aim 3: Examine associations between serum hormone levels and TMS-induced plasticity within and between sexes.

Key facts

Study ID

NCT07180654

Run by

University of Pennsylvania

People needed

100

Starts

2025-12-15

Expected to finish

2028-10-31

Last updated by the study team

2026-01-09

Who can join

Age: 20 and older, up to 40. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Able to give their consent
• If female, must have menstrual cycles of normal frequency, regularity, and duration.

You may not qualify if…

• Non-English speaking
• Any medical condition that increases risk for TMS
• History of seizure
• History of epilepsy
• Increased risk of seizure for any reason

Where it is running

• University of Pennsylvania — Philadelphia, Pennsylvania, United States (enrolling)

Full record on ClinicalTrials.gov

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