Research Into the Expression of the csgA-gene and How it Changes in Patients With Parkinson's Disease
Recruiting now
Conditions studied: Parkinsons Disease (PD)
In brief
This study seeks to understand the prevalence and variability of a gut bacteria gene called csgA in people with Parkinson's Disease. This understanding could inform development of potential new therapies targeting the gut in Parkinson's Disease.
Key facts
- Study ID
- NCT07175922
- Run by
- Vertero Therapeutics
- People needed
- 200
- Starts
- 2025-09-25
- Expected to finish
- 2026-03-30
- Last updated by the study team
- 2026-02-19
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Between 18-80 years of age at ICF signing (inclusive)
- A diagnosis of PD within 10 years from the time of ICF signing
- Current or history of gastrointestinal (GI) dysfunction or constipation based on screening assessment
- All participants must understand and provide written informed consent prior to any study specific procedures
- Able to speak, read, and understand study procedures in Dutch sufficiently to allow completion of all study assessments
You may not qualify if…
- Any known GI disorder if deemed clinically significant by the investigator. GI disorders may include, but are not limited to: Crohn's disease, ulcerative colitis, celiac disease, irritable bowel syndrome, or lactose intolerance
- Recent GI infection in the past 3 months if deemed clinically significant by the investigator.
- Major GI surgery (excluding appendectomy/cholecystectomy), such as bariatric surgery, gastrectomy, esophagectomy, vagotomy, small intestine surgeries, any type of colectomy, colostomy and anorectal surgeries if deemed clinically significant by the investigator
- Any known current or past eating disorder if deemed clinically significant by the investigator
- Use of systemic antibiotics within 6 months prior to enrollment
Where it is running
- Center for Human Drug Research — Leiden, Netherlands (enrolling)
Full record on ClinicalTrials.gov
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