QUAD-HF - Prospective Registry of Patients With Incident Heart Failure and Left Ventricular Ejection Fraction <50%

Recruiting now

Conditions studied: Heart Failure

In brief

The QUAD-HF registry is an observational study that would enroll patients in the United Kingdom, who have been newly diagnosed with heart failure and a left ventricular ejection fraction \<50%. We plan to assess clinical outcomes in these patients, such as hospitalization and death, in relation to their diagnosis, implementation of guidelines and type of treatments these patients have received.

Key facts

Study ID

NCT07174362

Run by

Mid and South Essex NHS Foundation Trust

People needed

4000

Starts

2025-10-06

Expected to finish

2031-11-01

Last updated by the study team

2025-12-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age >18 years
• Newly diagnosed Heart Failure with a Left Ventricular Ejection Fraction <50% (≤12 Weeks prior to enrolment).
• Able and willing to consent.

You may not qualify if…

• LVEF 50% or more at time of diagnosis
• Palliative care
• Unable or unwilling to give consent

Where it is running

• Mid and South Essex NHS Foundation Trust — Basildon, Essex, United Kingdom (enrolling)
• British Heart Foundation Glasgow Cardiovascular Research Centre, Glasgow — Glasgow, United Kingdom

Full record on ClinicalTrials.gov

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