The Effect of Bleaching Application Mode on Bleaching-induced Tooth Sensitivity.

Recruiting now · Not applicable

Conditions studied: Tooth Sensitivity

In brief

The aim of this study is to evaluate the effect of single versus multiple application protocols for in-office dental bleaching using two different bleaching gels (Pola Office Plus, SDI, 37.5% HP and Opalescence Boost, Ultradent, 40% HP) on the risk and intensity of tooth sensitivity, as well as the effect of the application protocol on the bleaching efficacy. Null hypothesis: There is no difference in intensity and risk of tooth sensitivity between single and multiple application of each gel and the application protocol dose not present significant effect on the bleaching efficacy.

Key facts

Study ID

NCT07173296

Run by

King Abdullah University Hospital

People needed

60

Starts

2025-01-01

Expected to finish

2026-09-30

Last updated by the study team

2025-09-15

Who can join

Age: 18 and older, up to 35. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• At least eight maxillary anterior teeth present.
• Age over 18
• The selected teeth have a mean shade of C2 or darker.
• Good general and oral health. (no visible plaque or gingivitis)
• No restorations or carious lesions on the buccal surfaces of the anterior teeth to be whitened
• No history of tooth sensitivity
• No use of a desensitizing agent or desensitizing toothpaste in the past six months
• No use of pain killer for the last 48 hours

You may not qualify if…

• Active caries and/or periodontal diseases (gingivitis and recession) or wasting diseases
• Smokers
• Pregnant/lactating women.
• Patients who have bleached their teeth previously.
• No schedule availability

Where it is running

• Jordan University of Science and Technology — Irbid, Jordan (enrolling)

Full record on ClinicalTrials.gov

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