A Study of V118E in Healthy Participants (V118E-003)
Recruiting now · Phase 1
Conditions studied: Healthy
In brief
Researchers are looking for new vaccines to prevent illnesses caused by a type of bacteria called Streptococcus pneumoniae. There are many different types of Streptococcus pneumoniae bacteria, called serotypes. Vaccines contain small parts of certain serotypes. These parts will not cause an infection but help the body create antibodies (proteins) to fight the bacteria. PREVNAR 20™ is a vaccine given to help to prevent disease from Streptococcus pneumoniae bacteria. Researchers designed a new vaccine, V118E, to help prevent disease from Streptococcus pneumoniae bacteria. The goal of this study is to learn how safe V118 formulation E is in Healthy Adults and how well people tolerate it.
Key facts
- Study ID
- NCT07168915
- Run by
- Merck Sharp & Dohme LLC
- People needed
- 126
- Starts
- 2025-10-08
- Expected to finish
- 2027-07-06
- Last updated by the study team
- 2026-07-15
Who can join
Age: 18 and older, up to 49. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- The main inclusion criteria include but are not limited to the following:
- Is in good health before randomization
You may not qualify if…
- The main exclusion criteria include but are not limited to the following:
- Has a history of invasive pneumococcal disease or known history of other culture-positive pneumococcal disease within 3 years prior to receiving study vaccination
- Has a history of clinically significant endocrine, gastrointestinal (GI), cardiovascular, hematological, hepatic, immunological, renal, respiratory, genitourinary, or major neurological (including stroke and chronic seizures) abnormalities or diseases
Where it is running
- Velocity Clinical Research, Hallandale Beach ( Site 0003) — Hallandale, Florida, United States (enrolling)
- Bio-Kinetic Clinical Applications, LLC dba QPS-MO ( Site 0004) — Springfield, Missouri, United States (enrolling)
- QPS-MRA, LLC-Early Phase ( Site 0002) — South Miami, Florida, United States
- University of Texas Medical Branch ( Site 0001) — Galveston, Texas, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.