Comparison of Two SpO2 Targets With Two Different Oximeters - Impact on FiO2 During Nasal High Flow Oxygen Therapy
Recruiting now · Not applicable
Conditions studied: Oxygen Delivery, Acute Respiratory Failure, High Flow Oxygen Therapy, Hypoxemic Acute Respiratory Failure
In brief
Several factors can influence oxygenation monitoring and respiratory support through oxygen therapy: the type of oximeter used, skin pigmentation, and the oxygenation target. It is essential to have an accurate measurement of SpO2 in order to optimize the flow of oxygen or FiO2 administered to patients. The question arises as to the impact of these confounding factors on the FiO2 set during high-flow nasal oxygen therapy. The aim of the study is to evaluate the impact of the oxygenation target and the oximeter used on FiO2 in patients receiving high-flow nasal oxygen therapy.
Key facts
- Study ID
- NCT07168213
- Run by
- Laval University
- People needed
- 30
- Starts
- 2025-10-21
- Expected to finish
- 2027-12-01
- Last updated by the study team
- 2026-03-09
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- ≥ 18 years of age
- Admiitted in intensive care unit
- Presence of an arterial catheter
- Ongoing on high flow nasal oxygen therapy with SpO2 between 88 and 100% with a FiO2 between 40 and 80% with the usual oximeter .
You may not qualify if…
- No SpO2 signal with oximeter in use
- False nails or nail polish
- Methemoglobinemia >0.015 on last available arterial gas
- Patient in isolation (multi-resistant bacteria, C-Difficile, SARS-CoV-2 ...)
- Expected to use another respiratory support within two hour of inclusion (NIV or mechanical ventilation)
Where it is running
- Institut universitaire de cardiologie et de pneumologie de Québec - Université Laval — Québec, Quebec, Canada (enrolling)
Full record on ClinicalTrials.gov
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