Postural Mobilization Compared to Noradrenaline Only in Off-Pump CABG Surgery
Recruiting now · Not applicable
Conditions studied: Coronary Artery Disease With Need for Bypass Surgery, Coronary Artery Disease(CAD), Coronary Artery Bypass, Off Pump Coronary Artery Bypass Graft, Off Pump Coronary Artery Bypass Surgery, Hemodynamic Management, Hemodynamic Optimization, Noradrenaline
In brief
This interventional prospective randomized study is designed to compare hemodynamic management using postural mobilization (+/- noradrenaline) versus noradrenaline only in patients undergoing open-heart coronary artery bypass graft (CABG) surgery.
Key facts
- Study ID
- NCT07163858
- Run by
- Infirmerie Protestante de Lyon
- People needed
- 50
- Starts
- 2025-10-06
- Expected to finish
- 2027-08-01
- Last updated by the study team
- 2025-12-03
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adult patient
- patient requiring isolated coronary bypass surgery
- Elective procedure or medical emergency
- First cardiac surgery
- Patient with an EF ≥30%
- Mandatory affiliation to a social security system
- Signed informed consent form
- Suspension of renin-angiotensin system inhibitors and angiontensn-neprilysin receptor blockers and sartans the day before surgical procedure
You may not qualify if…
- Contraindication to an inotropic substance (only NA will be used)
- Contraindication to passive leg raising
- Patient in a life-threatening emergency
- History of cardiac surgery
- Bilateral iliac or common femoral artery occlusion
- EF < 30%
- Pregnancy and breastfeeding
- Renal failure (GFR < 40 ml/min/1.73 m²)
- Patient with bilateral thigh amputation
- Class III obesity BMI > 40 kg/m²
Where it is running
- Infirmerie Protestante de Lyon — Caluire-et-Cuire, Auvergne-Rhône-Alpes, France (enrolling)
Full record on ClinicalTrials.gov
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