Personalized Theta-burst Stimulation for Long-lasting Changes in Approach/Avoidance Behavior
Recruiting now · Not applicable
Conditions studied: Approach/Avoidance Behavior
In brief
This study will assess the long-lasting effects of personalized theta burst stimulation (TBS), a repetitive form of transcranial magnetic stimulation (TMS), over the left prefrontal cortex on the approach/avoidance behavior. TBS will be personalized based on the prefrontal theta rhythm captured with electroencephalography (EEG). The main questions it aims to answer are: 1. does a single session of personalized TBS synchronized with the individual theta rhythm over the left prefrontal cortex results in the outlasting changes in the individual behavior? 2. Does TBS results in the brain rhythms' changes as measured using resting-state EEG?
Key facts
- Study ID
- NCT07161505
- Run by
- Northwestern University
- People needed
- 26
- Starts
- 2025-07-31
- Expected to finish
- 2026-08-31
- Last updated by the study team
- 2025-09-08
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Participants must be legal adults between the ages of 18 to 65;
- Able and willing to complete study procedures and tasks.
You may not qualify if…
- History or evidence of chronic neurological or mental disorder;
- Chronic condition that requires pharmacological treatment over the course of study participation;
- Pregnancy or breastfeeding;
- History or evidence of alcohol or drug addiction;
- Contraindications for transcranial magnetic stimulation (history of seizures, metallic or electric implant in the head/neck area);
- Contraindications for magnetic resonance imaging at 3 Tesla (non-compatible implants, metallic foreign bodies, insulin pump, pacemaker).
Where it is running
- Northwestern University Feinberg School of Medicine — Chicago, Illinois, United States (enrolling)
Full record on ClinicalTrials.gov
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