Effects of a Low Nicotine Standard and Tobacco Prices on Illegal Cigarette Purchasing

Recruiting now · Not applicable

Conditions studied: Cigarette Smoking, E-cigarette Use

In brief

This study will investigate the effects of a very-low-nicotine cigarette (VLNC) standard, e-cigarette price, and illegal cigarette price on illegal product purchasing and alternative product use in a virtual marketplace.

Key facts

Study ID

NCT07161050

Run by

Virginia Polytechnic Institute and State University

People needed

70

Starts

2025-12-01

Expected to finish

2026-10-07

Last updated by the study team

2026-01-16

Who can join

Age: 21 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Provide informed consent Be at least 21 years of age or older Provide a breath sample for measuring carbon monoxide (CO ≥ 8 ppm) Stable tobacco use patterns for at least two months

You may not qualify if…

• For exclusive cigarette smokers:
• Smoke at least 10 cigarettes daily and do not use NVPs regularly (no more than 9 times in the last month).
• For dual cigarette/NVP users:
• Smoke at least 10 cigarettes daily and use NVPs at least 3 times in a week (report use of closed nicotine salt system)
• For both groups:
• Have plans to move out of the area Have a serious or unstable physical or mental health condition Taking a tobacco cessation medication or medication that interferes with nicotine metabolism, motivation or reinforcement Report concrete, immediate plans to alter/quit using their usual nicotine products at the beginning of the study Being pregnant or lactating

Where it is running

• Fralin Biomedical Research Institute at Virginia Tech Carilion — Roanoke, Virginia, United States (enrolling)

Full record on ClinicalTrials.gov

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